Depression is like the plague. It spreads from one person to the next and when it gets to you, you're doomed. There's no real cure for depression; sure, you might find something that eases the pain, but when you're all alone in your bed late at night, you know in your heart that nothing is good anymore. Nothing is right. You're destined to feel this way for the rest of your life.
Depression is like being in love. It takes over your body; you can't eat, you can't sleep. It won't ever let you think about anything except how miserable you are. And much like love, the melancholy of depression is almost a good feeling. A safe feeling, at least. Because at least you fit somewhere, you're confined into a label, a word, an expression. "I'm depressed" like "I'm African-American" like "I'm Episcopalian" like "I'm hungry". It's a bit less than an emotion, but at least it's a bit more than an emptiness.
Depression is like perpetually trying to get to sleep. You think "Ok, now I'm going to sleep." You think "Ok, now I'm no longer depressed." And for a second you might believe that if you think it hard enough, it'll happen, but by then your train of thought has carried you far away and you're worse off than when you started.
Depression is like AIDS. It doesn't kill you, but it makes you so vulnerable to everything around you that in the end you'll die anyway. AIDS sufferers hate hearing their disease generalized as an "immune deficiency". Depression sufferers hate hearing their disease generalized as a "chemical imbalance". How dare they tell you that it's all in your mind, that all the pain and suffering and tears and cuts and bruises and screaming is all because something went off in your brain? Don't they know? How horrible you feel? How the world always seems like it's passing you by? Don't they know?
Depression is like procrastination. Always thinking that you should be doing something else, but instead you sit there, wrapped in your thoughts like in a blanket, waiting for something better to come along.
Depression is not natural.
Depression is a blessing in disguise.
Depression is a greater scourge than poverty.
Depression is a muse.
Depression is dead wrong.
Depression is a choice.
Depression is a demon.
Depression is ruining my life.
(Googlisms courtesy of googlism.com)